I would switch to 14/40 gearing with 18's anyways but it will not take anything considerable away from topend. You do not need higher octane with a 3* advance on a stock bike but double checking your jetting is always a good idea. The only specialty type tools you will need are a flywheel puller and dremel tool along with a way to measure mm's. Any performance hop up potentially effects reliability but by keeping your routein maintenance up and jetting correct its no more than adding a pipe to the bike.
i'm not gunna put a 14 t sproky because i'm racing a 250 gasgas and as i'm quicker in and out the bends all i want is a bit more go out the bends but i'm not gunna lose speed with a 3* advance