If you're getting the case welded, you can get it trenched for the +4 stroker crank.
The +3 vito's crank does not require machining.
The difference in power output is neglegible, however, the maximum power achievable is greater with the +4 because the way that Vito's makes the +3 able to be put in without machining is by making the big end of the crankshaft smaller in diameter to fit inside the cases. The +4 requires trenching but it uses the same size bearing as the factory crankshaft. While the vito's crank can take plenty of power it cannot take the ultimate built engine like the hot rods crank can.