So many variables 
How close to the razors edge are you?
Temperature
Humidity
Air pressure
Is the motor mild or wild
Can you afford to be wrong
Are you racing or playing
With lots of experience or an EGT gage you can avoid a meltdown.
Don't recall where I saw it, but it called for one size for every 1000'
So you would need 1/4 size bigger
Mikuni pocket jet calculator calls for one size for every 20* If it's 10* cooler from your "perfect" jetting
Add another 1/2 size
Phragle is right as to most power @
PERFECT jetting. You will feel the difference as you go from rich to perfect. Unfortunately as you go over the hump, two things happen. First, the power loss is barely noticeable even on a dyno. However the combustion temp rapidly increases. Do believe Phragle mentioned EGT of 1100* @ "perfect", Aluminum melts @ 1220*F. Do the math, not much room for error
