22x11x8

would they make any difference to the handling or suspension.
better, worse, no change
 
Depends on what 22" tire it is. What tire are you looking at?
Personally I like 20's on back to lower the center of gravity a tad to help handling.
 
yes, but may hit the heelgaurds
spend the few extra bucks and get at least 4 ply 20/21's
 
i have 20x11x8 holeshots on mine and they rubbed the heelguards when i slid sideways until i put my spacers on.